Example of biguanide is- 

Metformin 

Structure 



MOA 



Uses 

  1. Prediabetes: Metformin may prevent or delay the onset of diabetes in people with high blood sugar levels
  2. Gestational diabetes
  3. Polycystic ovary syndrome (PCOS)

Comments

Post a Comment

Popular posts from this blog

Classification of anti cancer agents with example Antineoplastic agents are drugs used to treat cancer by killing or stopping the growth of cancer cells.  They can be classified into different types based on their mechanism of action, such as : ALKYLATING AGENTs  Nitrogen Mustards : Chlorambucil   Ethylenimine: Thiotepa    Alkyl sulfonate : Busulfan    Nitrosoureas: Carmustine   Triazine : Dacarbazine   Methyl Hydrazine : Procarbazine    ANTIMETABOLITEs Folate Antagonist : Methotrexate  Purine Antagonist: 6-Mercaptopurine   Pyrimidine Antagonist : 5-Fluorouracil  PLATINUM Co-ODRINATION COMPOUNDs  Example : Carboplatin   ANTICANCER ANTIBIOTICs (Anthracycline)  Example: Doxorubicin & Daunorubicin 
Read more
Image
ANTIMETABOLITES  Antimetabolites are a type of chemotherapy drug that work by interfering with the DNA replication process in cancer cells. They mimic the structure of essential molecules that cancer cells need to replicate their genetic information and prevent them from creating the enzymes they need to divide.  These compounds are known as Antimetabolites because they inhibits the metabolic conversion of certain Chemicals (i.e. Folic Acid) to compounds which are essential for synthesis of DNA (Replication). 
Read more